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10.1096/BCF2024
Biology of Cilia and Flagella - 2024 (Conferences On-Demand)
May 12, 2024 - May 16, 2024
FREE. FASEB is pleased to make this conference freely available. We experienced technical issues that limited this conference to a portion of the speakers' presentations. Dive in and experience the same exceptional value we offer in our Conferences-on-Demand offering!
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May 12, 2024
Session 1 & Keynote: Structure and Function of Cilia and Flagella I
- Keynote: Cilia, Little Organelles with Big Roles in Development and Disease, Greg Pazour
These presenters have opted out of being recorded:
- Structure and Mechanism of lntraflagellar Transport, Anthony Roberts
- Visual Proteomics of Mammalian Cilia, Caitie McCafferty
- FLA4 Encodes a Putative Kinesin Binding Protein That Facilitates Anterograde IFT and Promotes Ciliary Assembly, Mary Porter
May 13, 2024
Session 2: Structure and Function of Cilia and Flagella II
- Armed and Disordered: Dissecting Radial Spoke Transport in Chlamydomonas, Karl Lechtreck
- KIF27 Couples Microtubule-Stabilizing Protein CEP162 to Promote Central Pair Integrity, Mu He
- Tracking Polycystin2 in Vivo, Courtney Haycraft
- Subcellular Spatial Proteomics by Microscopy-Guided Photo-Biotinylation Reveals Novel Protein Constituents in Primary Cilia, Jung-Chi Liao
These presenters have opted out of being recorded:
- Comparative Structural Study of Cilia and Flagella Across Diverse Organisms, Rui Zhang
- Nanoscale Architecture of the Respiratory Epithelium Reveals Cytoskeletal Fibers, Cytoplasmic Anchoring and Coupling to Ciliary Beating Forces, Aaron Vijayakumaran
- Spatiotemporal Dissection of Protein Localization to Human Primary Cilia, Jan Hansen
Session 3: Centrioles as Cilia Organizers
- Investigating the Trafficking Mechanisms of the Ciliary Vesicle, Kanie Tomoharu
- Ciliogenesis and Licensing of the GO Program, Rachel Turn
- An Alternative Cell Cycle Coordinates Multiciliated Cell Differentiation, Semil Choksi
- Atypical Choroid Plexus Nodal-like Cilia Display Unique Dynamics Throughout Lifetime, Annarita Patrizi
These presenters have opted out of being recorded:
- New Insights into Cilia Disassembly and Ciliopathies Revealed by Functional Genomic Screening, David Breslow
- Membrane Structure Remodeling on Mother Centriole During Ciliogenesis, Quanlong Lu
- Elongation Factor eEF1A Regulates Ciliary Assembly and Length by Mediating Dynamics of Axonemal Microtubules, Junmin Pan
May 14, 2024
Session 4: Cilia and Metabolic Disease
- Proteomic Analysis of Primary Cilia in Human Hypothalamic Neurons, Florian Merkle
- Obesity in Alstrom Syndrome: Molecular Insights from the ALMS1 Protein and Its Role in Primary Cilia, Phuong Thao Phan
- Pancreatic Beta Cell Cilia Form Physical Connections with Other Pancreatic Cell Types and Putative Synapses with Neurons, Nikolai Klena
- Prostaglandin E2 Regulates Adipogenesis in a Cilia-Dependent Manner, Mark Lee
These presenters have opted out of being recorded:
- Ciliary Hedgehog Signaling as Gatekeeper of Fatty Fibrosis, Daniel Kopinke
- Ciliary Arl13b Prevents Obesity in Mice, Tiffany Terry
- Mechanisms of Heterotaxy, Sigolene Meilhac
- A Microtubule Highway Mediates Cilium-to-Nuclear Signaling Transduction to Drive Cellular Senescence, Jinghua Hu
Session 5: Cilia in Neutral Systems
- Ciliary Intrinsic Mechanisms Regulate Dynamic Ciliary Extracellular Vesicle Release from Sensory Neurons, Juan Wang
- Primary Cilia Deconstruct as Granule Cell Neurons Develop, Carolyn Ott
These presenters have opted out of being recorded:
- Neuronal Primary Cilia Modulate Excitatory Synaptic Plasticity, Jiami Guo
- The Spare Domain Protein Test-1 and an Uncharacterized Secreted Protein Promote the Stereotyped Attachment of Neuronal Cilia to a Specific Glial Partner in C. Elegans, Max Heiman
Session 6: Cilia in Neutral Systems II
- Convergence of Autism Genes at the Cilium, Elina Kostyanovskaya
These presenters have opted out of being recorded:
- The Diversity of Cilia and Ciliary GPCRs in the Mouse Brain, Nick Berbari
- Organization of Sensory Neuron Cilia: How and Why, Pioli Sengupta
Session 7: Emerging Ciliated Organisms
- What Can the Unicellular Relatives of Animals Teach Us about Ciliary Biology, Flora Rutaganira
- Development of Ciliated Sensory Neurons and Feeding Behaviour During Whole Brain Regeneration in the Freshwater Planarian, Schmidtea mediterranea, Henrietta Bennett
These presenters have opted out of being recorded:
- Trafficking and Function of Flagellar Membrane Proteins in Leishmania Mexicana Parasites, Scott Landfear
- Axoneme Structure and Function in the Pathogen, Trypanosoma Brucei, Kent Hill
May 15, 2024
Session 8: Cilia Signaling
- How the Gli2 Transcription Factor Gets to the Cilium Tip for Hedgehog Signaling, Radhika Subramanian
- Interrogation of Cilia Force Sensing During Left-Right Patterning Via Optical Tweezers, Shiaulou Yuan
- Cilium Proteomics Revealed New Tricks of an Old Protein: Numb Regulates Hedgehog Signaling in the Ciliary Pocket, Xuecai Ge
- Loss of Kif 13b Causes Time-Dependent Changes in Ciliary Polycystin-2 Levels and Extracellular Vesicle Release, Lotte Pedersen
- Coordinated cAMP And AKAP Signaling by the Ciliary GPCR Gpr161, Saikat Mukhopadhyay
- Cilia are Wnt Signaling Organelles, Christof Niehrs
These presenters have opted out of being recorded:
- Ciliary PKA Signaling in the Hedgehog Cascade, Ben Myers
- The Human Ciliopathy Protein RSG1 Links the CPLANE Complex to Transition Zone Assembly, John Wallingford
Session 9: Cilia Signaling II
- Tak1/Map3k7, Tab2 And PKA-Ca Constitute a Novel Branch of TGFb/BMP Signaling in the Primary Cilium to Control Heart Development, Oskar Kaaber Thomson
- Dlg1 Functions Upstream of Sdccag3 and lft20 to Control Ciliary Targeting of Polycystin-2, Csenge Rezi
These presenters have opted out of being recorded:
- Sonic Hedgehog Signal Reception and Smoothened Allostery at the Primary Cilium, Stacey Odgen
- The Bbsome Regulates Ciliary Localization of Obesity-Associated Proteins MC4R and ADCY3, Gabriela Canales
- Targeted Signaling Modifiers for Dissecting the Function of Ciliary Cyclic AMP, Aldebaran Hofer
- Mechanisms of Smoothened Packaging into Extracellular Vesicles, Max Nachury, and Mingli Zhu
May 16, 2024
Session 10 & Keynote: Ciliopathies - Translation and Therapies
- lFT140-Mediated Retinal Dystrophy: Disease Modelling and Treatments, Julio Corral-Serrano
- Ciliary Gene Variants Are Associated with Diabetes Phenotypes in the General Population and Modulate Insulin Signaling in Cell Models of Disease, Theodore Drivas
- The Puzzle of Ofd1: One Gene, Several Disorders, Nunziana Pezzellla
These presenters have opted out of being recorded:
- Unravelling Therapeutic Approaches and Mechanisms for Nephronophthisis and Renal Ciliopathies, Sophie Saunier
- Heterozygous Missense and Truncation Variants in IFT-A Genes, IFT122, WDR19 and WDR35 Cause Autosomal-Dominant Polycystic Kidney Disease, Peter Czarnecki
- Loss of an Extensive Ciliary Connectiome Induces Proteostasis and Cell Fate Switching in Primary Ciliary Dyskinesia Caused by Ccdc39 and Ccdc40 Variants, Susan Dutcher
- Dysfunction of the Centrosomal Protein, CEP76, Is Associated with Syndromic Ciliopathies, Kamal Khan
Keynote 2 & Wrap-Up
This presenter has opted out of being recorded:
- Ciliopathies and Patient-Led Functional Genomics: Models, Mechanisms and Medicines, Pleasantine Mill
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Primary Organizer: Peter K. Jackson, PhD Professor Baxter Laboratory for Stem Cell Biology Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA
Pleasantine Mill, PhD Professor and Group Leader University of Edinburgh, Edinburgh, UK
Jeremy Reiter, MD, PhD Professor & Chair, Department of Biochemistry and Biophysics University of California School of Medicine, San Francisco, CA
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Chair: Mary Porter
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Tracking Polycystin2 in Vivo
August 27, 2024
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Chair: Barbara Tanos
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Ciliogenesis and Licensing of the G0 Program
August 27, 2024
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Chair: Maia Kinnebrew
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Chair: Shu-Hsien Sheu
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Primary Cilia Deconstruct as Granule Cell Neurons Develop
August 27, 2024
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Chair: Sarah Goetz
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Convergence of Autism Genes at the Cilium
August 27, 2024
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Chair: Stephen King
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Chair: Susan Detcher
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Cilia Are Wnt Signaling Organelles
August 27, 2024
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Chair: Keren Hilgendorf
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Chair: Jing Zhou
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The Puzzle of OFD1: One Gene, Several Disorders
August 27, 2024
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