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TGF-β Superfamily - 2024, Student Price
$150.00
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TGF-β Superfamily - 2024, Non-Conference Attendee Price
$300.00
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10.1096/TGFSRC2024
TGF-β Superfamily - 2024 (Conferences On-Demand)
July 21, 2024 - July 25, 2024
Since 1999, this unique SRC has been a venue for disseminating progressive and contemporary scientific research on TGF-β signaling for academic and industrial scientists. This conference will explore the latest developments in this discipline, ranging from the molecular complexities of signal transduction to biological responses during development and adult tissue homeostasis in health and disease. With nearly 25 years of bringing researchers together, it is also an exceptional opportunity to provide early-career investigators with a chance to network, learn, and collaborate with leaders in the field, with ample opportunities to present their work and develop their careers.
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July 21, 2024
Keynote Session
- BMP Signaling in Bone and Cartilage, Vicki Rosen
July 22, 2024
Session 1: Advances in Cancer/Immunology
- TGF-β in Squamous Cancer, Gareth Inman
- Activin Receptor-Like Kinase 1 Governs Monocytic Lineage Differentiation and Mobilization to Shape an Immunosuppressive Landscape in Breast Cancer Metastases, Kristian Pietras
- Foxp3 Induction and Maintenance in CD8 Regulatory T cells, Liliana C. Patiño Molano
- Targeting the TGFβ Axis to Tackle Resistance to Cancer Therapies, Rosemary Akhurst
- Structural Characterization of Selective Inhibitors of TGFβ1 Activation with Differing Mechanisms of Action and Clinical Potential, Chuck Streich Jr.
- GDF-15 Is a Critical Mediator of Treatment Resistance to Platinum-Based Chemoimmunotherapy, Thorsten Ross
- A New Mouse Model for Measuring TGF-β Responses, Lalage Wakefield
This presenter has opted out of being recorded:
- BMP Signaling and Transcription Factor Crosstalk in Myeloma Cell Apoptosis, Toril Holien
Session 2: Differentiation and Plasticity
- Activin B Is a Key Driver of Heterotopic Ossification in a Murine Model of Fibrodysplasia Ossificans Progressiva, Gregory Gipson.
- Mechanisms of Robust Developmental Patterning, Nathan Lord
- TGF-β Signaling in Liver, Pancreas, and Gastrointestinal Diseases, Lopa Mishra
- Using Self-Organizing Stem Cell Systems to Understand the Role of Nodal Signaling in Gastrulation, Aryeh Warmflash
These presenters have opted out of being recorded:
- Modulation of BMP Signaling, Lessons Learned from C. Elegans, Jun (Kelly) Liu
- TGF-β and RAS Jointly Unmask Primed Enhancers to Drive Metastasis, Jun Ho Lee
- New Aspects of TGFβ Signaling in Muscle Regeneration, Jérémy Kessler
July 23, 2024
Session 3: Signaling Mechanisms in Development and Cancer
- Contextual TGF-β Signaling, Joan Massagué
- Immunoglobulin Superfamily 1 Regulates Transforming Growth Factor-β Signaling to Control Skeletal Muscle Mass, Adam Hagg
- Structural Remodeling of the Endoplasmic Reticulum in Cell Growth and Survival, Hannah Ortiz
- Proteolytic Cleavage and Prodomain Function of BMP2 and BMP6 in Xenopus Embryos and Liver Endothelial Cells, Yongqiang Xue
- Cholesterol-dependent Modulation of TGF-β Receptor Complexes Mediates Hepatocellular Signaling Dynamics, Roohi Chaudhary
- TGF-β Induces Cholesterol Accumulation to Regulate the Fate of Tumor-Derived Extracellular Vesicles, Dorival Mendes Rodrigues-Junior
- Tumor Progression and TGF-β Signals, Carl Henrik Heldin
This presenter has opted out of being recorded:
- The role of SMAD1/5 Signaling in Breast Cancer Metastasis, Caroline Hill
Session 4: Regulatory Inputs into Reproductive Biology
- Deciphering the Molecular Mechanisms of SMAD Proteins in the Female Reproductive Tract, Zian Liao
- Discovery of the New Inhibin B Coreceptor, Dan Bernard
- Gonadal Inhibins: Gatekeepers of Female Fertility and Metabolic Health, Kelly Walton
- Structural Basis of Non-Latent Signaling by the Anti-Müllerian Hormone Procomplex, Drew Howard
This presenter has opted out of being recorded:
- Structural Diversity of TGF-β Signaling, Tom Thompson
Keynote Lecture
- Genetic Interrogation of TGF-β Receptors, Marty Matzuk
July 24, 2024
Session 5: Strategic Therapeutic Avenues
- Development of Novel Decoy Receptors, Lorena Lerner
- Recombinant Growth Differentiation Factor 11 (rGFD11) Improves Functional Outcomes in Rodent Models of Hemorrhagic and Ischemic Stroke, Tony Sandrasagra
- Early Detection of BMP9/10 Activity and Therapeutic Targeting the Disbalance in TGFb Signaling in Pulmonary Arterial Hypertension, Marie Jose Goumans
- Inhibiting Activin A Signaling in FOP, Aris Economides
- Small Molecule Targeting of ALK2, Alex Bullock
These presenters have opted out of being recorded:
- New Strategies to Antagonize TGF-β, Maureen O’Connor-McCourt
- Regulation of Stepwise Activin-A Precursor Processing and Its Role in Regulating Melanoma Growth, Daniel B. Constam
- Cell-type Specific Inhibition of TGF- β Signaling by TGM6, a Parasitic Protein That Mimics TGF-β Binding to TβRII, Andrew Hinck
Session 6: Dynamic Cross-Talk in Metabolism
- Model Organisms for Studying Metabolism, Michael O’Connor
- Human Genetic Insights into the Function of TGF-ß Superfamily Members in Human Physiology and Disease, Sam Lockhart
- Activin A: A Key Regulator of Fibroblast Function in Wound Repair and Tumorigenesis, Sabine Werner
- BMP Signaling Regulation of C. elegans Lipid Homeostasis in the Host-Pathogen Response, Kat Yamamoto
These presenters have opted out of being recorded:
- Acute Regulation of Adipose Tissue Lipolysis and Insulin Resistance by the TGFβ Superfamily Protein GDF3, Alex Banks
- Preserving Skeletal Muscle Mass and Enhancing Fat Loss by Targeting Activin Type II Receptors in Obesity, Paul Titchenell
July 25, 2024
Session 7: Neuroscience Connections
- Fine Tuning BMP Signaling, Kristi Wharton
- Age-Dependent and Cell-stage Dependent Role of TGF-β Signaling on Adult Neural Stem Cell Proliferation and Migration, Kierra Ware
- Low Blood Levels of Subforms of GDF11/8 Predict Higher Risk of Incident Cardiovascular, Dementia, and Mortality Events, Ryan Walker
- TGF-β Regulation of Astrocytes and Microglia, Agnes Luo
These presenters have opted out of being recorded:
- Dynamics and Interpretation of the BMP Signaling Gradient in Neural Tube Development, Anna Kicheva
- GDF11 as a Blood Factor That Increases Brain Blood Flow, Lee Rubin
- BMP Heterodimers Signal Via an Autocrine Pathway to Shape Phasic Innervation, Mihaela
Session 8: Organ Homeostasis
These presenters have opted out of being recorded:
- Molecular Basis by Which Parasite TGF- beta Mimics Elicit Cell-Type-Specific Signaling and Control Host Responses, Peter ten Dijke
- Mechanisms Underlying Unbalanced TGF-β Signaling in Human Disease, Gonzalo Sanchez-Duffhues
- Is BMP9 a Protective or Pathogenic Molecule in Pulmonary Arterial Hypertension? Paul Yu
- Molecular Pathogenesis of Vascular Proliferative Diseases, Akiko Hata
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Cathy Savage-Dunn, PhD: Professor, Queens College and the Graduate Center, CUNY, Flushing, NY
Tom Thompson, PhD: Primary Organizer, Professor, University of Cincinnati, Cincinnati, OH
Mytheye Karthikeyan, PhD: Associate Professor, The University of Alabama at Birmingham, Birmingham, AL
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Chair: Cathy Savage-Dunn
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BMP Signaling in Bone and Cartilage
September 13, 2024
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Chair: Gareth Inman
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TGF-β in Squamous Cancer
September 13, 2024 -
Foxp3 Induction and Maintenance in CD8Regulatory T Cells
September 13, 2024 -
A New Mouse Model for Measuring TGF-β Responses
September 13, 2024
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Chair: Mary Mullins
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Mechanisms of Robust Developmental Patterning
September 13, 2024 -
TGF-β Signaling in Liver, Pancreas, and Gastrointestinal Diseases
September 13, 2024
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Chair: Mythreye Karthikeyan
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Contextual TGF-β Signaling
September 13, 2024 -
Tumor Progression and TGF-βsignals
September 13, 2024
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Chair: Dan Bernard
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Discovery of the New Inhibin B Coreceptor
September 13, 2024
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Chair: Marty Matzuk
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Genetic Interrogation of TGF-β Receptors
September 13, 2024
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Chair: Tom Thompson
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Development of Novel Decoy Receptors
September 13, 2024 -
Inhibiting Activin A Signaling in FOP
September 13, 2024 -
Small Molecule Targeting of ALK2
September 13, 2024
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Chair: Michael O'Connor
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Model Organisms for Studying Metabolism
September 13, 2024
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Chair: Kristi Wharton
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Fine Tuning BMP Signaling
September 13, 2024 -
TGF-β Regulation of Astrocytes and Microglia
September 13, 2024
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