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Molecular Metabolism: Cells and Systems - 2024, Non-Conference Attendee Price
$300.00
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Molecular Metabolism: Cells and Systems - 2024, Student Price
$150.00
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10.1096/MMCSRC2024
Molecular Metabolism: Cells and Systems - 2024 (Conferences On-Demand)
July 14, 2024 - July 18, 2024
Since 1993, this conference has focused on the cloning and characterization of a subset of the major glucose transporter isoforms. It has since evolved to embrace emergent topics in metabolic control mechanisms as they relate to chronic diseases and conditions such as obesity, diabetes, and cardiovascular disease. This year’s meeting will bring together biochemists, cell biologists, physiologists, pharmacologists, and clinical investigators interested in metabolic diseases. The program will cover molecular metabolism which includes cellular biology, systems physiology, structural biology, and controlled clinical trials in human patients. Molecular metabolism as a discipline has made an astonishing resurgence, fueled by new data that place altered metabolic processes at the heart of several serious health problems beyond diabetes. These include Alzheimer’s, related dementias, cancers, cardiovascular diseases, and infections. This conference will provide a rare opportunity to bring together a diverse group of investigators for a week of intense discussion and discovery.
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July 14, 2024
Keynote Address
- Fueling Mitochondrial Efficiency by Fine-Tuning the Flames of Fat Oxidation, Deb Muoio
July 15, 2024
Session 1: Compartmentalizing Cell Metabolism: Spatial Mechanisms and Emerging
- Compartmentalization of Coenzyme Metabolism, Nathaniel Snyder
- Blueprint to Study the Entire Cellular Metabolic landscape in 2D and 3D, Ramon Su
- Metabolic Regulation of Protein Modification by Short-chain Fatty Acids, Emily Goldberg
- Molecular Basis for Intermediate Shuttling and Inhibition of Fatty Acid Synthase, Kollin Schultz
This presenter has opted out of being recorded:
- Metabolic Rewiring Driving Metastasis Formation, Sarah-Maria Fendt
Session 2: GLP1-Based Therapies: From Bench to Bedside and Beyond
- Innovation in Obesity Therapy: Current Status and Future Opportunities, James Trevaskis
- Therapeutic Opportunities to Preserve Muscle Mass and Function During Weight Loss, Paul Titchenell
- Glucagon Is a Complex Hormone, Jon Campbell
- Beyond GLP-1: Peptide Discovery in Metabolism and Physiology, Katrin Svensson
This presenter has opted out of being recorded:
- Development of Small Molecule PNPLA3-148M Degraders for the Treatment of MASLD and MASH, Gregory Tesz
July 16, 2024
Session 3: Navigating the Relationships Between Organ and Tumor Metabolism Session
- Linking Nuclear Branched-Chain Amino Acid Metabolism and Histone Propionylation in Pancreatic Cancer, Christina Demetriadou
These presenters have opted out of being recorded:
- Metabolic Reprogramming: A Bridge Between Aging and Cancer, Ana Gomes
- Tumor-Derived PTHrP Mediates Pancreatic Cancer Cachexia-Associated Adipose Tissue Wasting, Jason Pitarresi
- Tumor-Host Interactions Leading to Cachexia, Marcus Goncalves
- Amino Acid Acquisition in Cancer: Make It or Take, Gina DeNicola
Session 4: Cellular Organelles as Nutrient Sensors and Metabolic Signaling Hubs
- Exercise-Induced Signals Controlling Insulin Sensitivity and Metabolism in Type 2 Diabetes, Juleen Zierath
- Mitochondrial Copper Sensing via Metabolism and Signaling, Donita Brady
- Structural Insights into ATP-mediated Regulation of Lactate Dehydrogenase Activity, Aaron Leifer
These presenters have opted out of being recorded:
- Circadian and Thermogenic Control of Metabolite Transport in Adipocyte Mitochondria, Zach Gerhart-Hines
- Lactate Is Imported into the Mitochondria for Oxidation by MCT1, Gregory Ducker
- Unlocking the Potential of the Mammalian Electron Transport Chain, Jessica Spinelli
July 17, 2024
Session 5: Modulating Immunity with Metabolites
- Arginine Connects One-Carbon Metabolism to Histone Methylation in CAR T cells with Enhanced Metabolic Fitness and Anti-tumor Efficacy, Roddy O'Connor
- Innate Mitochondrial Checkpoints in Tumorigenesis, Fiachra Humphries
- Turning Up the Heat in the T Cell Immunometabolic Microenvironment, Jeff Rathmell
- The Guardians of Mitochondrial Metabolism, Solute Carrier SLC25 Family, Hongying (Hoy) Shen
These presenters have opted out of being recorded:
- Macrophage-Mediated Regulation of Adaptive Thermogenesis, Evanna Mills
- Mechanisms of Adipose Tissue Beiging, Silvia Corvera
Special Session: GLUT4ever: Past, Present and Future
- The Journey of Glucose in the Body, Through the Gut, Liver and into Muscle, Amira Klip
- Convergent Evolution of the GLUT4 Packaging Pathway in Mice and Humans, Frances Brodsky
- Connecting the Dots: PAT4's Role in Coordinating Insulin Signaling and Amino Acid Sensing for Glucose Uptake, Tim McGraw
Session 6: The Metabolic G7 (gut, liver, BAT, WAT, pancreas, kidney, muscle): Coordinating Solutions to Metabolic Challenges Part I
These presenters have opted out of being recorded:
- The Discovery of "Dual-Modal" Hepatocytes. Two Sides of the Same Coin, Jeff Pessin
- Adipocyte Thermogenesis and PPARG Regulation by the Autophagy Receptor NCOA4, Leslie Rowland
- Mechanisms of NAD+ Homeostasis in Aging and Disease, Melanie McReynolds
- Regulation of Organismal Metabolism by Brown Adipose Tissue, Paul Cohen
- Fatty Acid Metabolism in White Adipocytes during Lipolysis, Shannon Reilly
July 18, 2024
Session 7: The Metabolic G7: Coordinating Solutions to Metabolic Challenges Part II
- Toward a Whole-Body Flux Model of Mammalian Energy Metabolism, Tony (Sheng) Hui
- Glycerol Allosterically Activates Tissue Non-specific Alkaline Phosphatase, Lawrence Kazak
- Inter-Organ Crosstalk for Maintaining NAD+ Homeostasis, Won-Suk Song
- Disruption of a Bistable Regulation of Thermogenic Adipocytes During Aging, Annabel Wang
These presenters have opted out of being recorded:
- Mitochondrial Dynamics and Cardiometabolic Disease, Dale Abel
- Lactate Homeostasis Is Maintained by Suppression of Glycolysis and Lipolysis, Won Lee
Session 8: Nutrient Sensing Pathways That Control Metabolism
- Understanding the Interplay Between Diet, Acetyl-CoA Synthesis, and Hepatic Lipid Metabolism, Katy Wellen
- The Intracellular Citrate/Acetyl-CoA flux Is Mechanistically Linked to Autism Spectrum Disorder, Intellectual Disability and Progeria, Luigi Puglielli
- In Vivo Manganese Availability Determines Akt Activity, Jennifer Gamarro
- Chronic Urocortin 2 Administration Improves Exercise Capacity and Metabolism in Diet-Induced Obese Mice, Joseph Brozinick
- Guess Who’s Coming to Dinner, David James
These presenters have opted out of being recorded:
- A Multi-omics Approach to Finding Regulators of Fatty Acid Hydroxy Fatty Acids, Barbara Kahn
- Metabolite-Protein Architecture Identifies a Cysteine Shunt Controlling Liver Cholesterol, Haopeng Xiao
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Jeffrey Elmendorf, PhD: Associate Professor of Anatomy, Cell Biology and Physiology, Indiana University School of Medicine Center for Diabetes & Metabolic Diseases, Indianapolis, IN
David Guertin, PhD: Professor of Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, MA
Kathryn Wellen, PhD: Professor of Cancer Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA
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Chair: Chris Newgard
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Chair: Ralph Deberardinis
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Compartmentalization of Coenzyme Metabolism
September 17, 2024
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Chair: Joseph Brozinick
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Glucagon is a Complex Hormone
September 17, 2024 -
Beyond GLP-1: Peptide Discovery in Metabolism and Physiology
September 17, 2024
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Chair: Donita Brady
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Chair: Judith Simcox
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Mitochondrial Copper Sensing via Metabolism and Signaling
September 17, 2024
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Chair: Jessica Spinelli
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Innate Mitochondrial Checkpoints in Tumorigenesis
September 17, 2024 -
Turning up the Heat in the T Cell Immunometabolic Microenvironment
September 17, 2024
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Chair: Morris Birnbaum
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Chair: David James
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Toward a Whole-Body Flux Model of Mammalian Energy Metabolism
September 17, 2024 -
Inter-Organ Crosstalk for Maintaining NAD+Homeostasis
September 17, 2024
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Chair: Scott Summers
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In Vivo Manganese Availability Determines Akt Activity
September 17, 2024 -
Guess Who’s Coming to Dinner
September 17, 2024
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