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RNA Localization and Local Translation - 2024, Non-Conference Attendee Price
$300.00
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RNA Localization and Local Translation - 2024, Student Price
$150.00
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10.1096/RLLT2024
RNA Localization and Local Translation - 2024 (Conferences On-Demand)
July 07, 2024 - July 11, 2024
Since 1994, this SRC has provided a unique forum to share recent discoveries in subcellular mRNA localization and local translation. The conference is the best opportunity for scientists from diverse backgrounds including molecular and structural biology, cellular and developmental biology, neurobiology, and biophysics to network and collaborate on important research that can change lives. The intimate and inclusive format also focuses on providing young investigators and trainees to discuss, exchange ideas, and build new collaborations with experienced researchers. We particularly welcome participants from historically excluded groups. The program will focus on multi-disciplinary and multi-scale approaches to exploring the dynamic spatial organization and regulation of RNA metabolism in cells and tissues. The main themes will center around molecular mechanisms regulating mRNA transport, stability, and local translation. The program also will emphasize how cells harness RNA regulatory machinery to achieve tight spatial and temporal control of protein expression, and the contribution of these mechanisms to tissue organization and function. Topics will include long-standing questions related to RNA transport or translational control in health and disease, emerging concepts such as physical properties underlying RNA condensation or RNA hitchhiking on membranous organelles, as well as new technologies for discovery and analysis of localized RNAs and RNA-binding proteins or dynamic visualization of RNA metabolism.
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July 7, 2024
Session 1: Keynote 1
EMBO Keynote Lecture: Erin Schuman, Max Planck Institute for Brain Research - Transcriptomes and Proteomes at Synapses. This presenter has opted out of being recorded.
July 8, 2024
Session 2: Genomewide Approaches to Study Localized RNAs
- RNA Binding Proteins That Control RNA Localization, Gene Yeo
- Deciphering the RNA-Binding Protein Network During Endosomal mRNA Transport, Michael Feldbrügge
- Unraveling Subcellular mRNA Patterning in Gut Epithelium Using Proximity Biotinylation and Spatial Transcriptomics, Minkyoung Lee
- Control of RNA-Binding Proteins During Early Embryogenesis, Olivia Rissland
- The first global proximity mapping method, RNA-SPRITE, reveals drivers of RNA condensation and interaction specificity in neurons, Lindsay Becker
These presenters have opted out of being recorded:
- Discerning the Origins and Core Functions of Long Noncoding RNAs, Henry Krause
- Organelle-Specific Translation Atlas Revealed by APEX-Ribo-Seq, Kotaro Tomuro
Session 3: Organelle Associated RNAs
- RNA Localization in Centrosomes Ensures Mitotic Fidelity, Dorothy Lerit
- The Midbody and Midbody Remnant Are Assembly Sites for RNA and Localized Translation, Ahna Skop
- Conditional Mitochondrial mRNA Localization: Connecting Mitochondrial Composition to Growth and Metabolism, Brian Zid
These presenters have opted out of being recorded:
- The Unkempt RNA Binding Protein Reveals a Local Translation Program During Centriole Overduplication, Abe Martinez
- The Splicing Factor U2AF Regulates Translation and Localization of Nuclear-encoded Mitochondrial mRNAs in the Cytoplasm, Gloria Garcia
July 9, 2024
Session 4: RNA Localization Pathways and Mechanisms
- Distinct RNA Granule Types and Their Roles at the Synapse, Michael Kiebler
- A Role of the RNA Binding Protein IGF2BP3 in Determining the Left-Right Axis in Xenopus embryos, Joel Yisraeli
- Discrete Motifs in the Nanos 3'UTR Regulate RNA Accumulation in Drosophila Germ granules, Kira Mitchel
- m6A-Mediated RNA Localization in Neurons, Kate Meyer
- An Image-based RNAi Screen Identifies the EGFR Signaling Pathway as a Regulator of IMP/IGF2BP RNP Granules, Fabienne De Graeve
This presenter has opted out of being recorded:
- Molecular Mechanisms of mRNA Transport, Simon Bullock
- Dynamic Association Between Endosomes and mRNAs Drives Compartment-Specific mRNA Localization in Neurons, Ainhoa Viana Alzola
Session 5: RNA Granules/Condensates
- RNA Transport in the Cytoplasm: Biomolecular Condensates Drive mRNA Localization, Kim Mowry
- G3BP1 Promotes Intermolecular RNA-RNA Interactions During RNA Condensation, Dylan Parker
- Axoplasm Viscoelasticity and Pathological Protein Aggregation Are Modulated by Intracellular ATP in Mammalian Neurons, Marco Terenzio
- C. elegans Germ Granules Enrich Hundreds of Low Translation mRNAs with No Systematic Preference for Germ Cell Fate Regulators, Alyshia Scholl
- Close Encounters with Oskar: Proximity Proteomics of Germ Granule Interactions and Beyond, Kwan Yin Lee
This presenter has opted out of being recorded:
- Regulation of the Localization and Stability of Maternal RNAs by Intracellular Remodeling During Vertebrate Oocyte-to-Embryo Transition, Jin Yang
July 10, 2024
Session 6: RNA Metabolism and Disease
- Non-Nuclear Splicing Proteins and Local mRNA Processing in Axons and Dendrites, Corinne Houart
- Translating Discoveries with RNA, Robert Darnell
- TDP-43 Directly Inhibits Neurite RNA Accumulation, Matthew Taliaferro
- mRNA Targeting to the Dermal-Epidermal Junction Controls Epithelial Tissue Organization, Devon Mason
These presenters have opted out of being recorded:
- Association of Muscleblind-Like 1 RNA Binding Protein Domains with Kinesins and Endosomes Regulates mRNA Granule Trafficking, Gary Bassell
- Characterization of Biomolecular RNA Ensembles in Huntington's Disease, Sandra Fienko
Session 7: Keynote 2
The Role of RNA-Protein Condensates in Translation Regulation and Disease, Simon Alberti This presenter has opted out of being recorded.
July 11, 2024
Session 8: Translational Control
- The R2TP Chaperone Mediates Co-Translational Channeling of Quaternary Structure Formation, Edouard Bertrand
- Translational Regulation Through Association with a Biomolecular Condensate in Drosophila, Tim Weil
- Stress-Induced RNA Condensation Amplifies Translational Reprogramming, Jared Bard
- Regulation of Synapse Formation and Maintenance by RNA-Binding Proteins, Ulrich Hengst
- Dissecting Activity-Driven Synaptic RNA and Translational Regulation, Ezgi Hacisuleyman
- mRNA Translation in Glial Cytoplasmic Periphery Regulates Neuronal Synaptic Plasticity, llan Davis
- Mitochondrial Protein Heterogeneity Stems from the Stochastic Nature of Co-Translational Protein Targeting in Cell Senescence, Tatsuhisa Tsuboi
This presenter has opted out of being recorded:
- Circular RNA-derived Micropeptides at the Synapse: A New Mechanism of Localised Plasticity and Memory? Timothy Bredy
Session 9: New Technologies and Imaging
- A Rapid Inducible RNA Decay System Reveals Fast mRNA Decay in P-bodies, Bin Wu
- Quantitatively Mapping the Colocalization of Dendritic RNAs in Mouse Hippocampus: Insights from Highly Multiplexed Imaging, Renesa Tarannum
- Imaging the Life and Death of mRNAs in Single Cells, Jeff Chao
- Optogenetic Control and Roles of Membrane-Proximal mRNA Clusters, Kostas Moissoglu
These presenters have opted out of being recorded:
- Live Single-Transcript Imaging of mRNA Transport Dynamics in Developing Human Brain Organoids, Aileen-Diane Bamford
- Imaging Endogenous mRNAs Reveals Distinct Regulatory Pathways Underlying RNA Localization and Local Translation During Synaptic Plasticity, Sulagna Das
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Florence Besse, PhD: Group Leader, Université Côte d’Azur, Nice, France
Elizabeth Gavis, Primary Organizer: Princeton University, Princeton, NJ
Stavroula Mili, PhD: Senior Investigator, NIH, Bethesda, MD
Eric Wang, PhD: Associate Professor, University of Florida, Gainesville, FL
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Chair: Howard Lipshitz
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RNA Binding Proteins that Control RNA Localization
September 09, 2024 -
Control of RNA-Binding Proteins During Early Embryogenesis
September 09, 2024
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Chair: Sulagna Das
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RNA Localization in Centrosomes Ensures Mitotic Fidelity
September 09, 2024
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Chair: Matthew Tallaferro
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Distinct RNA Granule Types and Their Roles at the Synapse
September 09, 2024 -
m6A-Mediated RNA Localization in Neurons
September 09, 2024
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Chair: Geraldine Seydoux
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Chair: Michael Fainzilber
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Translating Discoveries with RNA
September 09, 2024 -
TDP-43 Directly Inhibits Neurite RNA Accumulation
September 09, 2024
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Chair: Tatjana Trcek
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Stress-Induced RNA Condensation Amplifies Translational Reprogramming
September 09, 2024
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Chair: Ilan Davis
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A Rapid Inducible RNA Decay System Reveals Fast mRNA Decay in P-bodies
September 09, 2024 -
Imaging the Life and Death of mRNAs in Single Cells
September 09, 2024 -
Optogenetic Control and Roles of Membrane-Proximal mRNA Clusters
September 09, 2024
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