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10.1096/LRMC2023
Lysophospholipid and Related Mediators: From Bench to Clinic - 2023 (Conferences On-Demand)
July 09, 2023 - July 13, 2023
This FASEB Science Research Conference (SRC) is focused on the biology of lysophospholipids, their receptors, and the methods developed to interrogate and modulate their functions for scientific insight and therapeutic benefit. The conference will bring together an interdisciplinary group of scientists from academia and industry who share a common interest in lysophospholipid biology.
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July 9, 2023
Keynote Lecture: Lysophospholipid G Protein-Coupled Receptors: Past, Present, and Future, Jerold Chun
Keynote Lecture: I Will Survive: S1P Signaling and T-Cell Survival, Susan Schwab
Session 1: Lysophospholipids in Neurobiology
- A Link Between Lipoproteins and Neuropathy, Christina Christofferson This video is not included in the FASEB Conferences On-Demand product.
- Targeting S1PR1 in Neuropathic Pain States, Daniela Salvemini
- Synaptic Lipids Alter Cortical Network Synchronization, Affecting Memory Formation and Stroke Outcome, Johannes Vogt
- Short Talk 1: Neuronal Contact Upregulates Astrocytic S1PR1 to Coordinate Astrocyte-Neuron Cross-Communication, Sandeep K Singh
July 10, 2023
Session 2: Lysophospholipids in Immunology and Inflammation
- Lysophosphatidylserines Derived from Microbiota in Crohn’s Disease Elicit Pathological Th1 Response, Hisako Kayama
- S1P Regulates the Recirculation of Tissue-Resident ILC2, Yuefeng (Tony) Huang
- Short Talk 2: PS-PLA1-LysoPS-PLS1 Axis in Infectious Immunity, Shun Yaginuma
Session 3: Lysophospholipids in Cancer
- Sphingosine-1-Phosphate: From Bench to Clinic, Sarah Spiegel
- Targeting Sphingolipid Metabolism in Combinational Cancer Therapies, Stuart Pitson
- Short Talk 3: Sphingosine Kinase 2 Regulates Non-Cell Autonomous Tumor Suppression Functions of p53 in the Tumor Microenvironment of Metastatic Breast Cancer, Cynthia Weigel
- Lysophosphatidylserine Receptor LPS1 Signaling Enhances the Anti-Tumor Immunity of Macrophages, Shun Nishikado
July 11, 2023
Session 4: Lysophospholipids in Cardiovascular Biology
- Erythrocyte S1P in Health and Disease, Yang Xia
- Sphingosine-1-Phosphate Receptors Regulate the Transendothelial Transport of HDL and LDL Contrariwise, Jerome Robert
- Short Talk 5: Erythrocyte Sphingolipid Metabolism Impacts Myocardial Ischemia Reperfusion Injury, Andrew Kuo
- Short Talk 6: Mapping S1PR1 Engagement and Ligand Dependence in the Vascular Network, Ilaria Del Gaudio
- Suppression of Endothelial Sphingolipid Metabolism and Signaling Contributes to Cardiometabolic Stress, Annarita Di Lorenzo
- Short Talk 7: Suppression of Sphingolipid Metabolism Mediates Endothelial Dysfunction and Contributes to Coronary Atherosclerosis in Mice, Onorina Laura Manzo This video is not included in the FASEB Conferences On-Demand product.
- Short Talk 8: Tonic S1P/S1PR3 Signaling in Vascular Smooth Muscle Cells Promotes Aoritc Aneurysm Rupture, Nathalie H. Schroder
Session 5: Lysophospholipids in Diabetes, Obesity, and Metabolic Syndrome
- S1P and Sphingolipid Metabolism in Central Control of Feeding, Sabrina Diano This video is not included in the FASEB Conferences On-Demand product.
- Adiponectin Receptors and Ceramidases in S1P-Mediated Cell Survival, William Holland
- Short Talk 9: Overexpression of OMRDL3 Confers Sexual Dimorphism in Diet-Induced Non-Alcoholic Steatohepatitis, Ryan D.R. Brown
- Short Talk 10: Interventions in S1P Metabolism as Modifiers of Susceptibility and Treatability of Metabolic Disorders, Melissa K. Nowak
- Short Talk 11: Dysregulated Sphingolipid De Novo Biosynthesis Contributes to Diabetic Cardiomyapthay and Vascular Dysfunction (Role of Metformim), Martina Smimmo
July 12, 2023
Session 6: Lysophospholipids in Drug Discovery, Diagnostics, and Clinical Trials
- S1P Pathobiology and Therapeutics, Timothy Hla
- Sphingosine Phosphate Lyase Insufficiency Syndrome: Prevalance, Prensentation, Pathophysiology, and Pharmacology, Julia Saba This video is not included in the FASEB Conferences On-Demand product.
- Consequences of S1P Transporter Inhibition, Webster Santos
- Short Talk 12: Gene Therapy for Lung Fibrosis with AAV9-SGPL1, Ranjha Khan
- LPA1 Antagonism in Lung Fibrosis, Ashfaq Parkar
- New Insights into Autotaxin: Structure, Function, and Therapeutic Targeting, Wouter Moolenaar
Session 7: Biochemistry and Cell Biology of Lysophospholipids and Their Receptors
- Genetic Screens to Trace Lysophingolipid Metabolism and Toxicity, Richard Proia
- Molecular Basis of Sphingosine-1-Phosphate (S1P) Transport and Signaling, Xiaochun Li
- Differential Activation Mechanisms of Lysolipid GPCRs by S1P or LPA, Shian Liu
- Cell-Surface Retention of Endothelial Sphingosine 1-Phosphate Receptor 1 Modulates the Signaling Efficiency, Hideru Obinata
July 13, 2023
Session 8: Lysophospholipids in Pathophysiology
- Role of Lysophosphatidic Acid Signaling Via LPA3 in Developing Lung Fibrosis, Junken Aoki
- Novel Insights into the Role of Autotaxin (ATX) in Bone Pathophysiology, Olivier Peyruchaud This video is not included in the FASEB Conferences On-Demand product.
- Short Talk 13: Search for the Endogenous Ligand of MrgB5 and MRGX4, Oxidized Phospholipid GPCRs Involved in Itch During Pruritic Skin Diseases, Yugo Takagi
- Short Talk 14: Targeting S1PR1 in the Central Nervous System Attenuates Chemotherapy-Induced Cognitive Impairment, Silvia Squillace
- Endothelial Cell S1PR1 Restrains VE-Cadherin Cleavage and Attenuates Experimental Inflammatory Arthritis, Nathalie Burg
- Therapeutic Value of S1PR3 Signaling in Clinical Pre-Sepsis, Markus Graler
Session 9: Novel Aspects of Lysophospholipid Signaling and Emerging Technologies
- Sphingosine-1-Phosphate in Red Blood Cell Biology, Bodo Levkau
- Lymphatic Endothelial Cell S1PR1 Regulates Tertiary Lymphoid Structure Formation in the Mesentery, Sathish Srinivasan
- Short Talk 16: LPA3 Signaling Alters Breathing Patterns by Activating Afferent Vagal Nerve, Masaki Nakamura
- Short Talk 17: S1P Distribution in Plasma of Septic Patients: Characterization Using Flow Induced Dispersion Analysis (FIDA), Isabelle Seidita
- Short Talk 18: Lysophosphatidic Acid Signaling Through LPA2 Suppresses Apoptosis of Spermatogenic Cells, Kuniyuki Kano
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Eric Camerer, PhD: Research Director, Paris Cardiovascular Center, Paris France
Annarita Di Lorenzo, PhD: Associate Professor, Weill Cornell Medicine, New York City, USA
Marcus Graler, PhD: Professor, Sepsis Research, Jena University Hospital, Jena, Germany
Satoshi Isshi, PhD: Professor, Department of Immunology, Akita, University Graduate School of Medicine, Japan
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Chairs: Jerold Chun and Kuniyuki Kano
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Targeting S1PR1 in Neuropathic Pain States
March 04, 2024
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Chairs: Junken Aoki and Cynthia Weigel
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PS-PLA1-LysoPS-LPS1 Axis in Infectious Immunity
March 04, 2024
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Chairs: Wouter Moolenaar and Richard Proia
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Sphingosine-1-Phosphate: From Bench to Clinic
March 04, 2024
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Chairs: Bodo Levkau and Nathalie Burg
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Erythrocyte S1P in Health and Disease
March 04, 2024
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Chairs: Annarita Di Lorenzo and Christina Christoffersen
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Chairs: Sarah Spiegel and Stuart Pitson
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S1P Pathobiology and Therapeutics
March 04, 2024 -
Consequences of S1P Transporter Inhibition
March 04, 2024 -
Gene Therapy for Lung Fibrosis with AAV9-SGPL1
March 04, 2024 -
LPA1 Antagonism in Lung Fibrosis
March 04, 2024
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Chairs: Julie Saba and Timothy Hla
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Chairs: Daniela Salvemini and William Holland
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Chairs: Susan Schwab and Yang Xia
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Sphingosine-1-Phosphate in Red Blood Cell Biology
March 04, 2024
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