November 10, 2024
This presenter has opted out of being recorded:
- Keynote 1: mTOR Signaling in Growth, Metabolism and Disease, Michael N. Hall
November 11, 2024
Session 1: Mechanisms of Hippo Pathway Regulation
These presenters have opted out of being recorded:
- Hippo-Yap/Taz Signaling Controls Cell Plasticity in Lung Secretorycells, Dae-Sik Lim
- Structure and Mechanism of Stripak in Hippo Signaling, Xuelian Luo
- Apical Polarity and Actomyosin Dynamics Control Kibra Subcellular Localization and Function in Drosophila Hippo Signaling, Richard Fehon
- Type Igamma Phosphatidylinositol Phosphate 5-kinase i5 Controls Hippo/yap Signaling, Chinmoy Ghosh
Session 2: Therapy and Resistance Factors in Cancers
- Adherent-to-Suspension Transition, Circulating Tumor Cells, and the Hippo Pathway, Hyun Woo Park
- Translational Mouse Models Identify Cancer Vulnerabilities After YAP/TAZ Inhibition, Marco Jessen
- YAP-TEAD Drive an Age-associated Gene Expression Program in Head and Neck Squamous Carcinomas, Anthony Spinella
This presenter has opted out of being recorded:
- The Multifaceted Enhancer-Regulation Roles of YAP/TEAD in Breast Cancer Progression, Zhijie Jason Liu
Session 3: Hippo Signaling in Stem Cells and Regeneration
- US -Hippo Signaling in Heart Regeneration, James F. Martin
These presenters have opted out of being recorded:
- RIPK4 Promotes Epidermal Differentiation Through Phase Separation and Activation of LATS1/2, Bin Zhao
- A Multifunctional Regulator of Yorkie and Focal Adhesions in the Drosophila Gut, Ken Moberg
November 12, 2024
Session 4: Regulatory Networks and Integration of Model Systems
- Coordinated Growth of Linked Epithelia Is Mediated by the Hippo Pathway, Iswar Hariharan
- YAP Activity Controls Proliferation Indirectly by Regulating the Cyclin D1/p27balance, Katie Ferrick
These presenters have opted out of being recorded:
- Transcription Factor Dynamics in Hippo Signaling, Kieran F. Harvey
- New Insights into Warts Regulation, Kenneth Irvine
- Fat Cadherin Regulation of Nuclear Signaling, Helen McNeill
Session 5: Transcriptional Regulation in Cancer and Beyond
- Dysregulation and Function of Hippo Signaling in Cancer Epithelial-Mesenchymal Transition, Jianrong Lu
These presenters have opted out of being recorded:
- The Role of Nuaks in Cancer and Fibrosis, Liliana Attisano
- The Complex Role of YAP and TAZ in Kidney Physiopathology, Fabiola Terzi
Session 6: Hippo Pathway in Rare/Pediatric Cancers
- CDK9 Inhibition by Dinaciclib Is a Therapeutic Vulnerability in Epithelioid Hemangioendothelioma, Brian Rubin
- Targeting Transcriptional Co-activators YAP1/TAZ in Fusion-positive Rhabdomyosarcoma Demonstrates a Novel Strategy in Ablating Transcriptional Programing of a Fusion-driven Sarcoma, Michael Deel
- The YAP/TAZ-TEAD Axis Promotes Tumor Stem Cell Functionality and Cellular Heterogeneity in Pediatric High-grade Gliomas, Renee Read
November 13, 2024
Session 7: Hippo Pathway and Cancer Microenvironment
- Investigating YAP-Dependent Reprogramming of Lipid Metabolism, Kristin Brown
- T3SS Secreted Effector of the Intracellular Bacteria Chlamydia Intersects with the Host Hippo Pathway, George F. Aranjuez
These presenters have opted out of being recorded:
- Development of a Pipeline to Evaluate YAP-TEAD inhibitors, Carsten G Hansen
- Roles of MAP4K in the Growth Control of the Liver and Squamous Epithelium, Zhipeng Meng
- YAP/TAZ are Crucial Regulator of Macrophage-mediated Pulmonary Inflammation and Fibrosis after Bleomycin-induced Injury, Manvendra Singh
- Yap Induces a Glycolytic Microenvironment to Promote Cardiac Fibrosis and Inflammation, Chang-Ru Tsai
Session 8: Broader Roles in Cancer Signaling
- Non-Canonical Regulation and Function of Hippo Signaling in Cancer, Jin Jiang
- Disrupting Bile Acid Metabolism by Suppressing FXR causes Hepatocellular Carcinoma Induced by YAP Activation, Yingzi Yang
- Targeting Transcription-Independent TEAD to Overcome Chemotherapy Resistance in YAP/TAZ Dispensable Cancer, Dong Hyeon Kim
This presenter has opted out of being recorded:
- Interrogating the Role of the ABL-Regulated TAZ-HIF1A-TEAD4 Complex in Brain Metastasis, Ann Marie Pendergast
November 14, 2024
Session 9: Drugging the Hippo Pathway in Cancer Treatment
- Targeting YAP/TAZ-TEAD for Potential Cancer Therapy, Wanjin Hong
- YAP/TAZ Regulates Adipocyte Plasticity, Leptin Production, and Systemic Energy Balance, Jae Myoung Suh
- Statins Inhibit TAZ-CAMTA1-Dependent Epithelioid Hemangioendothelioma Survival by Repressing the Mevalonate Pathway, John Lamar
These presenters have opted out of being recorded:
- Targeting TEAD by Small Molecule-Degraders, Jyoti Misra
- Selectivity of the First-in-Class Tead Auto-Palmitoylation Inhibitor VT3989, Tracy Tang
- Targeting the Hippo Pathway in Cancers, Thijs Hagenbeek
Session 10: Crosstalk with Other Pathways in Development and Diseases
- Hippo Signaling Interacts with TGFb Pathway to Regulate Pacemaker Cell State and Sinoatrial Node Fibrosis, Mingjie Zheng
- A Variable Early Phase of Adipogenesis Controlled by Transient YAP/TAZ Activation, Henri Berger
This presenter have opted out of being recorded:
- CG14767: A Novel Endocytic Regulator of Hippo Signaling, Alexey Veraksa