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Nuclear Bodies: Hubs of Genomic Activity - 2024, Student Price
$150.00
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Nuclear Bodies: Hubs of Genomic Activity - 2024, Non-Conference Attendee Price
$300.00
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10.1096/NBHGA2024
Nuclear Bodies: Hubs of Genomic Activity - 2024 (Conferences On-Demand)
June 02, 2024 - June 07, 2024
With a successful launch in 2022, this conference will continue to bring together investigators across the globe focusing on molecular biology, cell biology, and biophysics of bodies situated within the cell nucleus. These research subjects are considered separate from the chromosomes but operate in conjunction with the genome, including within pathological states, with this year’s conference focusing primarily on cancer topics. This conference will provide an opportunity for both early-career and experienced investigators to network, collaborate, and present their research. Organizers will craft a program that will include a large number of early-career researchers as speakers, session chairs, and/or poster presenters, with special emphasis on the inclusion of women and historically excluded groups.
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June 2, 2024
Keynote Lecture: A Novel Breast Cancer Springboarding from a Nuclear Body, David L. Spector
Session 1: Nuclear Bodies & Cancer I
- Therapeutic Targeting of RNA POL I Reveals an Unexpected Connection Between rRNA Synthesis and Splicing, Marikki Laiho
This presenter has opted out of being recorded:
- Novel Regulators of Enhanced Nucleolar Activity in Tumors, Maralice Conacci Sorrell
June 3, 2024
Session 2: NBs & Phase Separation
- Condensate-driven Interfacial Forces Reposition DNA Loci and Measure Chromatin Viscoelasticity, Amy R. Strom
- Cytoplasmic Forces Functionally Reorganize, Nuclear Condensates in Oocytes, Marie-Hélène Verlhac
- Nuclear Phase Separation Drives NPM1 Mutant Acute Myeloid Leukemia, Joshua A. Riback
- The Remodeling of Phase Separation in Tumorigenesis Via Super-Resolution Live Imaging, Dong Li
- Determinants and Consequences of Nucleolar Microenvironments, Matthew R. King
These presenters have opted out of being recorded:
- Transcriptional Control by Low-Complexity Domain Interactions at Single-molecule Resolution, Shasha Chong
- Structural Details of Helix-Mediated TDP-43, Oligomerization in RNA Processing, Nicolas L. Fawzi
- Metarrestin, a First-in-Class Small Molecule Targeting Cancer Metastasis, Disrupts Liquid Phase Separation and Effectively Stalls Ribosomal Biogenesis, Soumita De
Session 3: Form & Function of NBs
- Chaperoning the Chaperones: Proteomic Analysis of the SMN Complex Reveals Conserved and Etiologic Connections to the Proteostasis Network, A. Gregory Matera
- Cajal Body Composition, Assembly, and the Role of Dimethylarginine, Karla M. Neugebauer
- Uncovering a New Muscular Dystrophy: Recessive SNUPN Mutations Cause Spliceosomal Maturation and Cajal Bodies Defects, Nathalie Escande-Beillard
- Molecular Diversity Within the FET Protein Family: Unraveling Self-Association of the RNA-Binding Protein EWS, David S. Libich
- Drosophila Histone Locus Bodies: A Platform for Determining How Biomolecular Condensates Control Cell Cycle-Coupled Gene Expression, James P. Kemp Jr.
- The Nucleolar Granular Component Is Required for NAD Association with Nucleoli and the Establishment of Repressive Chromatin Architecture, Shivani Gupta
These presenters have opted out of being recorded:
- A Nuclear Body Assembly and Structure/Function Relationship, Miroslav Dundr
- New Approaches to Study Disordered Domains in Oncogenic Gene Regulation, Miguel N. Rivera
June 4, 2024
Session 4: Nuclear Bodies & Cancer II
- The Nucleolus, Micrornas and Human Evolution, Susan J. Baserga
- The EMBO Keynote Lecture: Genome Organization in and Around the Nucleolus, Raffaella Santoro
- The Role of the Paraspeckle in EWS-Activated Cancers, Renee Kinne
These presenters have opted out of being recorded:
- Exploring Human Nucleolar Organizers by Precision Chromosome Engineering, Brian McStay
- Pol I Transcription and Pre-rRNA Processing Are Closely Coordinated and Pre-rRNA Plays a Key Role in Maintaining the Nucleolar Structure, Sui Huang
- Nuclear Body Formation During Inflammatory Stimulation of Macrophages, Paul D. Kaufman
Session 5: Career Development Workshop
- Pair Up: A Unique Diversity Mentoring Program in Cell Biology, George M. Langford
June 5, 2024
Session 6: RNA & Nuclear Bodies
- Molecular Dissection of Single-Locus Nuclear Microcompartments, David M. Shechner
- FRG2A Is Part of a Novel Family of lncRNAs Affecting Nucleolus-Associated Chromatin Interactions and Function in FSHD Cells, Francesca Losi
- Unveiling the Role of Transcription Factor in the Regulation of Sex-Specific Alternative Splicing, Mukulika Ray
- Coordination of Nuclear RNA Processing by Speckle-Localized Kinase TAOK2, Bridget E. Begg
These presenters have opted out of being recorded:
- Nuclear Long Non-coding RNAs Are Involved in 3D Genome Structure and Super-enhancer Activity in Breast Cancer, Noriko Saitoh
- Hypoxia Responsive Gene Expression Is Controlled by Spatial Organization of Chromatin and Nuclear Domain-Enriched lncRNA, Kannanganattu V. Prasanth
- De Novo Assembly of Nuclear Stress Bodies Restrain Acute Inflammatory Responses, Ling-Ling Chen
- Building Tools to Probe Condensate Functions in Space and Time, Sofia Quinodoz
- Keynote Speaker: PML: From Leukemia to Phase Transition and SUMOylation Control, Hugues de Thé H
Session 7: New RNA-Based Technologies
- Harnessing R2 Retroelement Machinery and RNA-only Delivery for Site-Specific Safe-Harbor Transgene Addition to the Human Genome, Kathleen Collins
- This Ottr Be Good: Detection of miRNA-Target Pairs Inside the Nucleolus Via an Optimized Experimental Workflow, Hadi Najafi
- Cancelled - Charting a Future for Sequencing RNA and Its Modifications: A National Academies Report, Susan J. Baserga
- Hypothesis-free Discovery of the Subcellular Proteome: A Total-Sync Ultra-Content Microscopic Opto-Biotinylation System, Mei Zhang
June 6, 2024
Session 8: NBs & Gene Expression
- Nuclear Organization of Gene Expression Near Nuclear Speckles and Surrounding Structures, Andrew Belmont
- 3D Genome Organization Around Nuclear Speckles Drives mRNA Splicing Efficiency, Mitchell Guttman
- Clamp-Mediated Chromatin Domain Formation Affects Transcription, Joseph Aguilera
- Regulation of Ribosomal RNA Transcription in Different Mammalian Cell Types, Vikram R. Paralkar
- The Mute Button: Turning Down the Volume of Histone Gene Expression, Mark Geisler
- Interplay of Condensation and Chromatin Binding Underlies BRD4 Targeting, Claire Weaver
This presenter has opted out of being recorded:
- RNA Binding Nuclear Speckle Proteins Form Intrinsic and RNA-Dependent Microphases, Min Kyung Shinn
Session 9: Nuclear Scaffolding Factors
- US ZNF692, A Novel Nucleolar Scaffold, M. Carmen Lafita-Navarro
- Identification of Coilin Interactors Reveals New Regulators of Cajal Body Number and Substructure, Chuyue Zhang
These presenters have opted out of being recorded:
- Regulation of Nucleolar Ribosomal RNA Transcription by Cell-Type-Specific Hematopoietic Transcription Factor, Charles Antony
- SUMO Promotes DNA Repair Protein Collaboration to Support Alterative Telomere Lengthening Without PML, Huaiying Zhang
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Ling- Ling Chen, PhD: Group Leader, Shanghai Insititute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai, China
Erica Larschan, PhD: Richard and Edna Salomon Associate Professor of Biology, Brown University, RI
Greg Matera, PhD: Professor, University of North Carolina, Chapel Hill, NC
Thoru Pederson, PhD: Primary Organizer, Arnett Professor of Cell Biology, University of Massachusetts Chan Medical School, Worcester, MA
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Keynote by David L. Spector
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Chair: Joseph Aguilera
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Chair: Isabella Brown
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Chair: Claire Weaver
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Chair: Chuyue Zhang
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The Nucleolus, Micrornas and Human Evolution
August 19, 2024 -
The Role of the Paraspeckle in EWS-Activated Cancers
August 19, 2024
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Introduction by Thoru Pederson
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Chair: Renee Kinne
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Chair: Arlene P. Levario
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Chair: Francesca Losi
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Chair: Christina Dollinger
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ZNF692, a Novel Nucleolar Scaffold
August 19, 2024
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